Telling us about your ethnicity is important because certain variants are more common in certain ethnicities. Many reports explain your results in the context of your ethnicity. You can learn more about how this applies to each type of report below:
Genetic Health Risks*
Our Genetic Health Risk reports provide information about variants that can increase your risk for certain conditions. The studies that identified these variants are often performed with people of a homogeneous ethnic group. The reports provide information about risk in the context of ethnicities that have been studied. If your ethnicity has not been studied, we are not able to provide tailored risk information for you. The effect of the variant(s) in the report is still expected to be similar, but the exact risk numbers are not well understood.
Genetic conditions affect certain ethnicities more often than others. Our reports provide more detailed information for ethnicities that have been well studied. The About Condition section of the report lists all ethnicities that the condition is common in, and the "About Test" section only lists ethnicities that our test is relevant for.
These reports provide information on studies performed in populations of a specific, homogeneous ethnic background. The results in these reports may not apply as well to people of other ethnicities. Please refer to the About Test section of each Wellness report for information on applicable ethnicities.
Our Traits reports can provide you with results based on your genetic information paired with your self-reported ethnicity. As certain variants are more common in certain ethnicities, we are able to better personalize your reports in the context of your ethnicity.
Keep in mind that our reports are not comprehensive for all ethnicities.
*The 23andMe PGS test uses qualitative genotyping to detect clinically relevant variants in the genomic DNA of adults, from saliva collected using an FDA-cleared collection device (Oragene·DX model OGD-500.001) for the purpose of reporting and interpreting genetic health risks. The relevance of each report varies based on ethnicity. Our genetic health risk reports describe if a person has variants associated with a higher risk of developing a disease, but do not describe a person’s overall risk of developing the disease. The reports are not intended to diagnose any disease, tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication or how much of a medication you should take.
**The 23andMe PGS test uses qualitative genotyping to detect clinically relevant variants in the genomic DNA of adults, from saliva collected using an FDA-cleared collection device (Oragene·DX model OGD-500.001) for the purpose of reporting carrier status and reporting and interpreting genetic health risks. The relevance of each report varies based on ethnicity. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future or anything about the health of your fetus, or your newborn child's risk of developing a particular disease later in life. For Gaucher Disease Type 1, we provide a single report that includes information on both carrier status and genetic health risk