If you have just received your 23andMe® reports, you may be wondering where to start. After all, there is a lot about you that makes you unique. In this article you will find a brief introduction to the reports provided by 23andMe and other key information to help you get started exploring your genetics.
If you are new to the world of genetics or it has been a while since your last genetics class, you can review a few concepts about genetics in our Tutorials.
This article will discuss the following topics:
- Accessing your account.
- How to set your profile information (applicable to Health + Ancestry Service profiles only).
- How to print a summary of your reports.
- The 23andMe report categories and the information each category provides.
- The limitations of the reports (applicable to Health + Ancestry Service profiles only).
After you receive an email announcing “Your data is ready to view”, you will need to log in to your online 23andMe account using the email address you provided during the registration process—this is the same email address used to announce that your data was ready.
Your 23andMe reports and our interactive tools are only accessible from within your account.
- If you forgot the password connected to your account, you can reset it here.
- If you forgot or lost access to the email address connected to your account, please contact us.
This section is applicable to the Health + Ancestry Service.
After you have successfully logged into your account, you are asked to supply your ethnicity. Our Carrier Status* and Traits reports explain your results in the context of your ethnicity. Some associations between genotype and phenotype are better studied in certain populations and are most applicable to people of a particular ethnic background. If a genetic condition or trait has been studied in your ethnicity, our reports may provide more detailed information for you. As new scientific studies are published, we’ll continue working to expand our tests to include variants applicable to more ethnicities.
You can review or edit your ethnicity information at any time from within your account.
We do not use your self-reported ethnicity information to compute your ancestry composition.
You will be asked to choose whether you would like to include or exclude all Carrier Status* and Genetic Health Risk* reports. Our health reports provide information about genetic risks for health conditions that could be relevant for you, your children, and potentially other family members. Deciding whether or not you want to learn about these risks is a personal choice. You have control over what types of information you would like to see and can choose to exclude certain reports that you may not want to view. You can review important information about our Genetic Health Risk and Carrier Status reports.
If you choose to exclude these reports, you can choose to include them at a later time from within your account settings. You will also have the choice to remove these reports from view at a later time, however, please remember that once you have viewed your genetic information, the knowledge is irrevocable.
It is important to note that reports on wellness and traits are always visible for profiles that purchased the Health + Ancestry Service.
Reports Requiring Additional Opt-in
The Late-onset Alzheimer’s Disease Report* and Parkinson’s Disease Report* require you to make an additional choice after you have agreed to receive health reports. If you tend to feel anxious or have ever been diagnosed with anxiety or depression, you may have more emotional difficulty with these reports. To learn more about the disease and report, click the “Learn more” link next to the title of the report on the reports configuration page.
If you choose to exclude these reports, you will have the option to include them at a later time from within your account settings.
The 23andMe reports are only accessible from within your account; you must log in to your account to print your reports. To print an individual report, click on the Print button in the upper-right corner of the report.
To print a summary of your reports, simply login and select All Reports from the Reports dropdown menu, then click on the Report Summary button in the upper-right corner.
You can explore what your DNA says about you in the 23andMe Reports—accessible from the top navigation bar or the side panel of your homepage. The categories of reports available to you depend on your service type—Ancestry Service or Health + Ancestry Service. Learn more.
- Learn about the 23andMe Ancestry reports (Ancestry Composition, Haplogroups, Neanderthal Ancestry, and Your DNA Family)
- Learn more about the 23andMe Carrier Status, Genetic Health Risk, Wellness or Traits reports
Explore what your DNA can tell you about your origins and your ancient ancestors with our Ancestry reports. In your DNA, we can find genetic traces of where your ancestors lived throughout history.
The Ancestry Composition report uses DNA you inherited from recent ancestors on both sides of your family and tells you the proportion of your DNA that comes from each of 31 worldwide populations, offering a detailed view of your ancestry. The Ancestry Composition results reflect where your ancestors may have lived before ocean-crossing ships and airplanes came on the scene. Learn more.
The Haplogroup reports can shed light on the origins of some of our ancestors and on their migrations over tens of thousands of years. Your maternal haplogroup assignment tells you about your maternal-line ancestors, from your mother through her mother and beyond. If you are male, your paternal haplogroup tells you about your paternal-line ancestors, from your father to his father and beyond. Haplogroups are assigned by detecting certain genetic variants unique to each haplogroup. Learn more.
The Neanderthal Ancestry report tells you if parts of your DNA can be traced back to Neanderthals. Neanderthals were ancient humans who interbred with modern humans before becoming extinct 40,000 years ago. Learn more.
Your DNA Family
The Your DNA Family report tells you about the diverse group of 23andMe customers who have DNA in common with you and how many these DNA Relatives you have around the world. Learn more.
The 23andMe Carrier Status* reports tell you about variants that may not affect your health, but could affect the health of your future family. Being a "carrier" means you "carry" one genetic variant for a condition. Carriers do not typically have the genetic condition, but they can pass a genetic variant down to their children. Understanding your carrier status helps you work with your doctor to prepare for the health of your future family.
Genetic Health Risk
The 23andMe Genetic Health Risk* reports tell you if you have genetic variants associated with an increased risk of developing certain health conditions - such as Late-Onset Alzheimer's Disease* or Parkinson's Disease*. While having a particular variant can be linked to a higher risk for a condition, it does not necessarily mean you will develop the condition. It is important to remember that these reports do not cover all possible genetic variants that could influence risk for these conditions and that other non-genetic factors, such as environment and lifestyle, can also influence risk for these conditions.
The 23andMe Wellness reports can help you make more informed choices that may relate to healthy living. Find out why some people may weigh more than others on diets that are high in saturated fat. You can also learn how your DNA may influence your caffeine consumption, lactose digestion and your muscle type.
Our Traits reports are a fun way to explore how your DNA makes you unique, from your food preferences to physical features.
You will receive the Ancestry reports—Ancestry Composition, Haplogroups, Your DNA Family, and Neanderthal Ancestry. You will also have access to interactive tools to share, compare and discover more with friends and family—including the DNA Relatives tool.
Health + Ancestry Service
You will receive 75+ reports on carrier status*, genetic health risk*, wellness, traits and ancestry. You will also have access to interactive tools to share, compare, and discover more with friends and family—including the DNA Relatives tool.
Is 23andMe diagnostic?
No, 23andMe reports do not diagnose any health conditions or provide medical advice. The 23andMe Carrier Status reports can tell you if you have specific genetic variants that you could pass on to your children, from saliva collected using a collection device (Oragene DX model OGD.500.001), but they cannot tell you if you have two copies of the variants. Carrier Status tests are not intended to diagnose a disease, or tell you anything about your risk for developing a disease in the future. Each Carrier Status report is most relevant for people of certain ethnicities. On their own, these tests are not intended to tell you anything about the health of your fetus, or your newborn child’s risk of developing a particular disease later in life.
The 23andMe Genetic Health Risk reports tell you if you have genetic variants that are associated with an increased risk of developing certain health conditions but does not report on your a user’s entire genetic profile. While having a particular variant can be linked to a higher risk for a condition, it does not necessarily mean you will develop the condition. It is important to remember that these reports do not cover all possible genetic variants that could influence risk for these conditions and that other non-genetic factors, such as environment and lifestyle, can also influence risk for these conditions. Consult with a healthcare professional if: the condition runs in your family, you think you might have the condition, or you have questions about any genetic or nongenetic risk factors you may have.
The 23andMe Wellness reports make connections between your DNA that may relate to healthy living, however, other genetic and nongenetic factors may affect whether or not you display a specific trait. Consult with a healthcare professional before making any major lifestyle changes.
The 23andMe Trait reports make connections between your DNA and your features and characteristics. It is important to keep in mind that although these reports predict your genetic chances of having a trait, many other factors can influence your actual traits.
Receiving "Variant not determined" or "Result not determined"
In some cases, we are not able to provide a result for a particular report. If results cannot be provided for a report, you will see “Variant not determined” or “Result not determined”. If you are seeing this result, our algorithm may not have been able to confidently determine your genotype. All genetic markers used in our reports are evaluated for high data quality and accuracy. Occasionally, a person's data may not allow us to determine his or her genotype confidently at a particular marker. Some “not determined” variants are expected in the raw data and not a cause for concern.
It is important to keep in mind that our tests do not diagnose any health conditions. Our reports can help you understand your chances of carrying a variant that could be passed down, however 23andMe does not report if someone has two copies of a tested variant.
Understanding Your Genetic Health Risk Reports
To understand what your genetic results mean or to better understand the limitations of the report, navigate to the Frequently Asked Questions section of the report. This section is located near the top of each report.
- 23andMe Sign In
- DNA Basics (tutorial)
- Printable summary
- Ancestry Composition report
- Maternal Haplogroup report
- Paternal Haplogroup report
- Neanderthal Ancestry report
- Your DNA Family report
- Carrier Status reports
- Genetic Health Risk reports
- Wellness reports
- Traits reports
- Locate and connect with relatives using the DNA Relatives tool
- Share your reports with family members or friends
- Access your uninterpreted, raw genetic data
- Conditions not included in the 23andMe reports
- Sample status information
*The 23andMe PGS test uses qualitative genotyping to detect clinically relevant variants in the genomic DNA of adults from saliva collected using a collection device (Oragene·DX model OGD-500.001) for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. The relevance of each report varies based on ethnicity. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. These reports are not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication or how much of a medication you should take. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future or anything about the health of your fetus, or your newborn child's risk of developing a particular disease later in life. For Gaucher Disease Type 1, we provide a single report that includes information on both carrier status and genetic health risk. The Late-onset Alzheimer’s Disease genetic health risk report is indicated for reporting of the ε4 variant in the APOE gene and describes if a person has a variant associated with an increased risk of developing late-onset Alzheimer’s disease. The ε4 variant included in this report is found and has been studied in many ethnicities. Detailed risk estimates have been studied the most in people of European descent. The Parkinson’s Disease genetic health risk report (i) is indicated for reporting of the G2019S variant in the LRRK2 gene, and the N370S variant in the GBA gene, (ii) describes if a person has variants associated with an increased risk of developing Parkinson’s disease, and (iii) is most relevant for people of European, Ashkenazi Jewish, and North African Berber descent.